Flora Jessop was born and raised in Colorado City, Arizona. She was raised in a polygamous family, with two mothers and twenty-seven siblings, all members of the Fundamentalist Church of Jesus Christ of Latter-Day Saints (FLDS).
When she was sixteen years old, after years of abuse, including being impregnated by her own father and being forced to marry her first cousin, Phillip Jessop, she fled her family and faith. After many years as a vagabond in Middle and Southwest America, Jessop finally sought legal justice, and was awarded $10,000 in a lawsuit against the State Of Arizona for failing to protect her from the abuse she suffered.
Jessop finally settled in Galena, Kansas where she soon met a man named Tim and created a family unit with him and their daughters, Shauna and Megan. Tim's mother, Carol, would eventually reintroduce Jessop to Christianity. Jessop's divorce from her cousin Philip was finalized in 1995.
In February 2001, Jessop and Tim married in Baxter Springs, Kansas. In April 2001, her younger sister Ruby was forced to marry her stepbrother, Haven Barlow. The ceremony, officiated by Warren Jeffs, would be the catalyst that turned Jessop into an advocate against child abuse in the FLDS community. She helped, in a large part, to create the Child Protection Project.
Flora is the cousin-by-marriage of Carolyn Jessop, another former FLDS member who wrote Escape, an autobiographical account of her upbringing in the polygamist sect and later flight from that community.
Flora has been active since the early 2000s in anti-child abuse work particularly focusing on the plight of women and children in the FLDS. She founded an organization, "Help the Child Brides" (later dissolved) and later joined "Child Protection Project" with fellow activist Linda Walker.
Jessop is the author of a book, Church of Lies, telling her personal story. She says (in the book), that her goal is not only end child abuse in polygamous cults, but to give a name to all child abuse victims in the United States.