Larry Patrick Levis was born in Fresno, California, on September 30, 1946. His father was a grape grower, and in his youth Levis drove a tractor, pruned vines, and picked grapes in Selma, California. He earned a bachelor's degree from Fresno State College (now California State University, Fresno) in 1968, a master's degree from Syracuse University in 1970, and a Ph.D. from the University of Iowa in 1974.
Among his honors were a YM-YWHA Discovery Award, three fellowships in poetry from the National Endowment for the Arts, a Fulbright Fellowship, and a Guggenheim Fellowship.
Levis died of a heart attack in 1996, at the age of 49.