“The thing is, I don’t know if these stories he was telling were mine, or his, or someone else’s. You spend your life among words, listening, making sense out of what you say and out of what you imagine other people are saying to you, believing that something in particular happened like this or that, as a result of this or that, with these or those consequences. But it is never so simple, is it? I suppose that if we read about ourselves in a book, we wouldn't recognize ourselves, we wouldn't realize that those people doing certain things and behaving in a particular manner are us. I always believed that I knew Alejandro, that I knew him intimately, I mean, the way you might know a doll you've once taken to pieces. But it wasn't true.”

“The idea tells you everything. Lots of times I get ideas, I fall in love with them. Those ones you fall in love with are really special ideas. And, in some ways, I always say, when something's abstract, the abstractions are hard to put into words unless you're a poet. These ideas you somehow know. And cinema is a language that can say abstractions. I love stories, but I love stories that hold abstractions--that can hold abstractions. And cinema can say these difficult-to-say-in-words things. A lot of times, I don't know the meaning of the idea, and it drives me crazy. I think we should know the meaning of the idea. I think about them, and I tell this story about my first feature Eraserhead. I did not know what these things meant to me--really meant. And on that particular film, I started reading the Bible. And I'm reading the Bible, going along, and suddenly--there was a sentence. And I said, forget it! That's it. That's this thing. And so, I should know the meaning for me, but when things get abstract, it does me no good to say what it is. All viewers on the surface are all different. And we see something, and that's another place where intuition kicks in: an inner-knowingness. And so, you see a thing, you think about it, and you feel it, and you go and you sort of know something inside. And you can rely on that. Another thing I say is, if you go--after a film, withholding abstractions--to a coffee place--having coffee with your friends, someone will say something, and immediately you'll say “No, no, no, no, that's not what that was about.” You know? “This is what it was about.” And so many things come out, it's surprising. So you do know. For yourself. And what you know is valid.”

“Some may say that such a girl is not ready for a relationship with a man, especially a man in his late sixties. But to that I say: We don't know anything. We don't know how to cure a cold or what dogs are thinking. We do terrible things, we make wars, we kill people out of greed. So who are we to say how to love. I wouldn't force her. I wouldn't have to. She would want me. We would be in love. What do you know. You don't know anything. Call me when you've cured AIDS, give me a ring then and I'll listen.”

“I will never be a brain surgeon, and I will never play the piano like Glenn Gould.But what keeps me up late at night, and constantly gives me reason to fret, is this: I don’t know what I don’t know. There are universes of things out there — ideas, philosophies, songs, subtleties, facts, emotions — that exist but of which I am totally and thoroughly unaware. This makes me very uncomfortable. I find that the only way to find out the fuller extent of what I don’t know is for someone to tell me, teach me or show me, and then open my eyes to this bit of information, knowledge, or life experience that I, sadly, never before considered.Afterward, I find something odd happens. I find what I have just learned is suddenly everywhere: on billboards or in the newspaper or SMACK: Right in front of me, and I can’t help but shake my head and speculate how and why I never saw or knew this particular thing before. And I begin to wonder if I could be any different, smarter, or more interesting had I discovered it when everyone else in the world found out about this particular obvious thing. I have been thinking a lot about these first discoveries and also those chance encounters: those elusive happenstances that often lead to defining moments in our lives.[…]I once read that the definition of insanity is doing the same thing over and over and expecting different results. I fundamentally disagree with this idea. I think that doing the same thing over and over and expecting different results is the definition of hope. We might keep making mistakes but the struggle gives us a sense of empathy and connectivity that we would not experience otherwise. I believe this empathy improves our ability to see the unseen and better know the unknown.Lives are shaped by chance encounters and by discovering things that we don’t know that we don’t know. The arc of a life is a circuitous one. … In the grand scheme of things, everything we do is an experiment, the outcome of which is unknown.You never know when a typical life will be anything but, and you won’t know if you are rewriting history, or rewriting the future, until the writing is complete.This, just this, I am comfortable not knowing.”

“I realize that a certain school of thoughtsays that who we are is something we construct for ourselves. We build ourselves out of what we think we remember, what we believe to be true about our life; and the possessions we gather around us are supposedly a part of this, that we are, to some extent what we own.”

“She wouldn't say what we both knew. 'The reason you will not say it is, when you say it, even to yourself, you will know it is true: is that it? But you know it is true now. I can almost tell you the day when you knew it is true. Why won't you say it, even to yourself?' She will not say it.”