“Doctors of Science, what is man that heShould hope to come to a good end? The best is not to have been born.”

“Are you really surprised by the endurance of religion? What ideology is likely to be more durable than one that conforms, at every turn, to our powers of wishful thinking? Hope is easy; knowledge is hard. Science is the one domain in which we human beings make a truly heroic effort to counter our innate biases and wishful thinking. Science is the one endeavor in which we have developed a refined methodology for separating what a person hopes is true from what he has good reason to believe. The methodology isn't perfect, and the history of science is riddled with abject failures of scientific objectivity. But that is just the point-these have been failures of science, discovered and corrected by-what, religion? No, by good science.”

“You...you've been here quite a long time, haven't you?"What? Oh...yes. Ever since I married What's-her-name. Uh, Martha. Even before that. Forever. Dashed hopes, and good intentions. Good, better, best, bested. How do you like that for a declension, young man?”

“To be good is an unnatural condition. There is no man that is born knowing what humility is, what kindness and compassion and hope and love and generosity are. These are things that must be learned. Learned through trials and through pain and through suffering; held onto every inch of the way. Good is not born, it is made”

“Good God, man, what is that smell?" He eyed with disgust the doctor's filthy cloak."Life," answered the doctor.”

“Human misery must somewhere have a stop; there is no wind that always blows a storm; great good fortune comes to failure in the end. All is change; all yields its place and goes; to persevere, trusting in what hopes he has, is courage in a man. The coward despairs.”