“The stage lost a fine actor, even as science lost an acute reasoner, when [Holmes] became a specialist in crime.”

“I am lost without my Boswell.[Sherlock Holmes on Dr. Watson.]”

“I think that I had better go, Holmes.""Not a bit, doctor. Stay where you are. I am lost without my Boswell.”

“I must thank you,' said Sherlock Holmes, 'for calling my attention to a case which certainly presents some features of interest. I had observed some newspaper comment at the time, but I was exceedingly preoccupied by that little affair of the Vatican cameos, and in my anxiety to oblige the Pope I lost touch with several interesting English cases.”

“Detection is, or ought to be, an exact science and should be treated in the same cold and unemotional manner. You have attempted to tinge it with romanticism, which produces much the same effect as if you worked a love-story ... Some facts should be suppressed, or, at least, a just sense of proportion should be observed in treating them. The only point in the case which deserved mention was the curious analytical reasoning from effects to causes, by which I succeeded in unravelling it.''—Sherlock Holmes on John Watson's "pamphlet", "A Study in Scarlet".”

“Man, or at least criminal man, has lost all enterprise and originality. As to my own little practice, it seems to be degenerating into an agency for recovering lost lead pencils and giving advice to young ladies from boarding-schools.”

“Holmes, you have an answer to everything”