“Addiction to alcohol is also a neurological phenomenon, the result of a complex set of molecular alterations that take place in the brain when it’s excessively and repeatedly exposed to the drug. The science of addiction is complicated, but the basic idea is fairly straightforward: alcohol appears to wreak havoc on the brain’s natural systems of craving and reward, compromising the functioning of the various neurotransmitters and proteins that create feelings of well-being.”

“Trying to describe the process of becoming an alcoholic is like trying to describe air. It's too big and mysterious and pervasive to be defined. Alcohol is everywhere in your life, omnipresent, and you're both aware and unaware of it almost all the time, all you know is you'd die without it, and there is no simple reason why this happens, no single moment, no physiological event that pushes a heavy drinker across a concrete line into alcoholism. It's a slow, gradual, insidious, elusive becoming.”

“So it persists, for many of us, hunger channeled into some internal circuitry of longing, routed this way and that, emerging in a thousand different forms. The diet form, the romance form, the addiction form, the overriding hunger for this purchase or that job, this relationship or that one. Hunger may be insatiable by nature, it may be fathomless, but our will to fill it, our often blind tenacity in the face of it, can be extraordinary.”

“Passivity is corrosive to the soul; it feeds on feelings of integrity and pride, and it can be as tempting as a drug.”

“The great anxious focus on the minutiae of appetite—on calories and portion size and what's going into the body versus what's being expended, on shoes and hair and abs of steel—keeps the larger, more fearsome questions of desire blurred and out of focus. American women spend approximately $1 million every hour on cosmetics. This may or may not say something about female vanity, but it certainly says something about female energy, where it is and is not focused. Easier to worry about the body than the soul, easier to fit the self into the narrow slots of identity our culture offers to women than to create one...that allows for the expression of all passions, the satisfaction of all appetites. The great preoccupation with things like food and shopping and appearance, in turn, is less of a genuine focus on hunger—indulging it, understanding it, making decisions about it—than it is a monumental distraction from hunger.”

“Love—the desire to love and be loved, to hold and be held, to give love even if your experience as a recipient has been compromised or incomplete—is the constant on the continuum of hunger, it's what links the anorexic to the garden-variety dieter, it's the persistent pulse of need and yearning behind the reach for food, for sex, for something.”

“When you hear nothing about the body, he suggests, you stop listening to it, and feeling it; you stop experiencing it as a worthy, integrated entity.”