“Many of the big changes of the next 25 years will come from unknowns working in their bedrooms and garages...”

“Puberty was 25 years ago and I’m still waiting for my voice to change.”

“Last year we had many smallish hopes, made many smallish attempts, suffered many smallish failures, and we died one by one. This year a change of plan! One big hope, one big push, one big fuck-up, and we all die at once.”

“The true test of any scholar's work is not what his contemporaries say, but what happens to his work in the next 25 or 50 years. And the thing that I will really be proud of is if some of the work I have done is still cited in the text books long after I am gone.”

“The tragedy of Tupac is that his untimely passing is representative of too many young black men in this country....If we had lost Oprah Winfrey at 25, we would have lost a relatively unknown, local market TV anchorwoman. If we had lost Malcolm X at 25, we would have lost a hustler named Detroit Red. And if I had left the world at 25, we would have lost a big-band trumpet player and aspiring composer--just a sliver of my eventual life potential.”

“From year to year, and from age to age, we see [biologists] at work, adding no doubt much to the unknown, and advancing many important interests, but, at the same time, doing little for the establishment of comprehensive views of nature. Experiments in however narrow a walk, facts of whatever minuteness, make reputations in scientific societies; all beyond is regarded with suspicion and distrust.”