“Experiements that have been devised to inflict even mild social pain (like exclusion form a group task or betrayal by a partner in a gambling game) have demonstrated significant activation of the sinula and the anterior cingulate cortex. Emotional pain isn't just a metaphor: In terms of brain activation, it partially overlaps with physical pain.”

“The worst pain in the world goes beyond the physical. Even further beyond any other emotional pain one can feel. It is the betrayal of a friend.”

“Studies have found that the same areas in the brain that light up in imaging scans when we break a leg are activated when we split up with our mate. As part of a reaction to a breakup, our brain experiences the departure of an attachment figure in a similar way to that in which it registers physical pain.”

“Many animals experience pain, anxiety and suffering, physically and psychologically, when they are held in captivity or subjected to starvation, social isolation, physical restraint, or painful situations from which they cannot escape. Even if it is not the same experience of pain, anxiety, or suffering undergone by humans- or even other animals, including members of the same species- an individual's pain, suffering, and anxiety matter.”

“The beauty of physical pain is that it wipes out the other forms of pain.”

“The conversation was dangerous for it was designed to incite physical violence and, if left to continue, might have succeeded. But the pain Ranulf first wanted to inflict was humiliation, and that could not be achieved with fists.It required intellect.And maybe a slight emotional push.”