“Antidepressants. The thought of this girl actually being depressed made me want to grab the whole planet and throw it into the sun. Well, more than usual anyway.”

“Psychotherapy works for the treatment of depression, and the benefits are substantial. In head-to-head comparisons, in which the short-term effects of psychotherapy and antidepressants are pitted against each other, psychotherapy works as well as medication. This is true regardless of how depressed the person is to begin with. Psychotherapy looks even better when its long-term effectiveness is assessed. Formerly depressed patients are far more likely to relapse and become depressed again after treatment with antidepressants than they are after psychotherapy. As a result, psychotherapy is significantly more effective than medication when measured some time after treatment has ended, and the more time that has passed since the end of treatment, the larger the difference between drugs and psychotherapy.”

“For people who are depressed, and especially for those who do not receive enough benefit from medication of for whom the side effects of antidepressants are troubling, the fact that placebos can duplicate much of the effects of antidepressants should be taken as good news. It means that there are other ways of alleviating depression. As we have seen, treatments like psychotherapy and physical exercise are at least as effective as antidepressant drugs and more effective than placebos. In particular, CBT has been shown to lower the risk of relapsing into depression for years after treatment has ended, making it particularly cost effective.”

“God's plan is usually pretty great. It is a whole lot better than mine anyway. I am so glad that He does not allow me to win.”

“embracing one's wholeness makes life more demanding--because once you do that, you must live your whole life. One of the most painful discoveries I made in the midst of the dark woods of depression was that a part of me wanted to stay depressed. As long as I clung to this living death, life became easier; little was expected of me, certainly not serving others.”

“You're the most annoying girl on the planet. You make me want to throw myself off a bridge. And, unfortunately, I am one hundred percent, head-over-heels, crazy in love with you.”