“But happiness is a difficult thing-it is, as Aristotle posited in The Nicomachean Ethics, an activity, is is about good social behavior, about being a solid citizen. Happiness is about community, intimacy, relationships, rootedness, closeness, family, stability, a sense of place, a feeling of love. And in this country, where people move from state to state and city to city so much, where rootlessness is almost a virtue ("anywhere I hang my hat...is someone else's home"), where family units regularly implode and leave behind fragments of divorce, where the long loneliness of life finds its antidote not in a hardy, ancient culture (as it would in Europe), not in some blood-deep tribal rites (as it would in the few still-hale Third World nations), but in our vast repository of pop culture, of consumer goods, of cotton candy for all-in this America, happiness is hard.”

“After a while, meaning and implication detach themselves from everything. One can be a father and assume no obligations, it follows that one can be a boyfriend and do nothing at all. Pretty soon you can add friend, acquaintance, co-worker, and just about anyone else to the long list of people who seem to be part of your life, though there is no code of conduct that they must adhere to. Pretty soon, it seems unreasonable to be bothered or outraged by much of anything because, well, what did you expect? In a world where the core social unit - the family - is so dispensable, how much can anything else mean?”

“It doesn’t matter how many years go by, how much therapy I embark on, how much I try to achieve that elusive thing known as perspective, which is supposed to put all past wrongs into their rightful and diminished place, that happy place where all the talk is of lessons learned and inner peace. No one will ever understand the potency of my memories, which are so solid and vivid that I don’t need a psychiatrist to tell me they are driving me crazy. My subconscious has not buried them, my superego has not restrained them. They are front and center, they are going on right now.”

“Sometimes it feels like we're all living in a Prozac nation. The United States of Depression. ”

“The trouble is that when we get around to solutions, it always seems to come down to Prozac. Or Zoloft. Or Paxil. Deep clinical depression is a disease, one that not only can, but probably should, be treated with drugs. But a low-grade terminal anomie, a sense of alienation or disgust and detachment, the collective horror at a world that seems to have gone so very wrong, is not a job for antidepressants. The trouble is, the big-picture problems that have so many people down are more or less insoluble: As long as people can get divorced they will get divorced; America=s shrinking economy is not reversible; there is no cure for AIDS. So it starts to seem fairly reasonable to anesthetize ourselves in the best possible way. I would like so much to say that Prozac is preventing many people who are not clinically depressed from finding real antidotes to what Hillary Clinton refers to as 'a sleeping sickness of the soul,' but what exactly would those solutions be? I mean, universal health care coverage and a national service draft would be nice, but neither one is going to save us from ourselves. Just as our parents quieted us when we were noisy by putting us in front of the television set, maybe we're now learning to quiet our own adult noise with Prozac. ”

“I mean, if you were to find a shattered mirror, find all the pieces, all the shards and all the tiny chips, and have whatever skill and patience it took to put all that broken glass back together so that it was complete once again, the restored mirror would still be spiderwebbed with cracks, it would still be a useless glued version of its former self, which could show only fragmented reflections of anyone looking into it. Some things are beyond repair. And that was me.”

“I need to start thinking more like an engineer and less like a scientist: I need to think about what works, not about why.The problem was me. I was it.That's what I believed. I believed I was the everything.The largeness of my disaster dragged others- frankly, everyone- down with me. I was certain that entire rooms of people became vertiginously joyous when I was high and having fun, and that anyone who got near me when I was morose and coming down would have to feel my pain as potently as I did. Whether I was high or low, the intensity was so great and the world became so small- no larger than the size of me and my mood of the moment- that it was hard to imagine that anything else was going on. It was hard to believe that there were things happening in the world that were not about me.”