“Depression is about as close as you get to somewhere between dead and alive, and it's the worst.”

“Nothing about art is a waste of time. "It's the time wasting that gets you somewhere.”

“...between addiction and depression? Depression a lot worse. Depression ain't something you just get OFF of. You can't get CLEAN from depression. Depression be like a bruise that never goes away. A bruise in your MIND. You just got to be careful not to touch where it hurts. It always be there, though.”

“A one night stand with the perfect girl is like... it's like getting to the airport in Hawaii, then getting right back on the plane and flying home. It's depressing to have been that close to paradise without actually getting there.”

“People get sick and sometimes they get better and sometimes they don't. And it doesn't matter if the sickness is cancer or if it's depression. Sometimes the drugs work and sometimes they don't. Sometimes the drugs work for a while and then they stop. Sometimes the alternative stuff works and sometimes it doesn't. And sometimes you wonder if no outside interference makes any difference at all; if an illness is like a storm, if it simply has to run its course and, at the end of it, depending on how robust you are, you will be alive. Or you will be dead.”

“One thing I learned, between addiction and depression? Depression a lot worse. Depression ain't something you just get off of. You can't get clean from depression. Depression be like a bruise that never goes away. A bruise in your mind. You just got to be careful not to touch where it hurts. It always be there, though.Darlene, in The Marriage Plot”