“Getting help for substance abuse can be reduced to the deceptively simple focus of ‘keeping away from the dope.’ But what does getting help with depression mean? Learning to keep away from your own mind?”

“In a typical mental health catch-22, the alienating nature of depression tends to keep its sufferers from finding their way to the very support groups that might help them.”

“How can you hide from what never goes away? --Heraclitus”

“The trouble is that when we get around to solutions, it always seems to come down to Prozac. Or Zoloft. Or Paxil. Deep clinical depression is a disease, one that not only can, but probably should, be treated with drugs. But a low-grade terminal anomie, a sense of alienation or disgust and detachment, the collective horror at a world that seems to have gone so very wrong, is not a job for antidepressants. The trouble is, the big-picture problems that have so many people down are more or less insoluble: As long as people can get divorced they will get divorced; America=s shrinking economy is not reversible; there is no cure for AIDS. So it starts to seem fairly reasonable to anesthetize ourselves in the best possible way. I would like so much to say that Prozac is preventing many people who are not clinically depressed from finding real antidotes to what Hillary Clinton refers to as 'a sleeping sickness of the soul,' but what exactly would those solutions be? I mean, universal health care coverage and a national service draft would be nice, but neither one is going to save us from ourselves. Just as our parents quieted us when we were noisy by putting us in front of the television set, maybe we're now learning to quiet our own adult noise with Prozac. ”

“Depression gave me more then just a brooding introspection. It gave me humor, it gave me a certain what-a-fuck-up-I-am shtick to play with when the worst was over..the side effects, the by products of depression, seems to keep me going. I had developed a persona that could be extremely melodramatic and entertaining. It had, at times, all the selling points of madness, all the aspects of performance art. I was always able to reduce whatever craziness I’d experienced into the perfect antidote, the ideal cocktail party monologue...I thought this ability, to tell away my personal life as if it didn’t belong to me, to be queerly chatty and energetic at moments that most people found inappropriate, was what my friends liked about me.”

“If you are chronically down, it is a lifelong fight to keep from sinking ”

“Depression is about as close as you get to somewhere between dead and alive, and it's the worst.”