“So many more cycles of elation of the first kiss, and devastation when it's over.”

“The atypically depressed are more likely to be the walking wounded, people like me who are quite functional, whose lives proceed almost as usual, except that their depressed all the time, almost constantly embroiled in thoughts of suicide even as they go through their paces. Atypical depression is not just a mild malaise...but one that is quite severe and yet still somehow allows an appearance of normalcy because it becomes, over time, a part of life. The trouble is that as the years pass, if untreated, atypical depression gets worse and worse, and its sufferers are likely to commit suicide out of sheer frustration with living a life that is simultaneously productive and clouded by constant despair. It is the cognitive dissonance that is deadly. Because atypical depression doesn’t have a peak- or, more accurately, a nadir, like normal depression, because it follows no logical curve but instead accumulates over time, it an drive its victim to dismal despair so suddenly that one might not have bothered to attend to treatment until the patient has already, and seemingly very abruptly, committed suicide.”

“The trouble is that when we get around to solutions, it always seems to come down to Prozac. Or Zoloft. Or Paxil. Deep clinical depression is a disease, one that not only can, but probably should, be treated with drugs. But a low-grade terminal anomie, a sense of alienation or disgust and detachment, the collective horror at a world that seems to have gone so very wrong, is not a job for antidepressants. The trouble is, the big-picture problems that have so many people down are more or less insoluble: As long as people can get divorced they will get divorced; America=s shrinking economy is not reversible; there is no cure for AIDS. So it starts to seem fairly reasonable to anesthetize ourselves in the best possible way. I would like so much to say that Prozac is preventing many people who are not clinically depressed from finding real antidotes to what Hillary Clinton refers to as 'a sleeping sickness of the soul,' but what exactly would those solutions be? I mean, universal health care coverage and a national service draft would be nice, but neither one is going to save us from ourselves. Just as our parents quieted us when we were noisy by putting us in front of the television set, maybe we're now learning to quiet our own adult noise with Prozac. ”

“I am so tired of the girl in the infirmary, I am so sick of the girl who cries wolf all the time - even though not one of those cries was ever a false alarm. Not one of my pleas was ever less than truly urgent because when it's all in your mind, there always IS a wolf.”

“Jesus, I wondered, what do you do with pain so bad it has no redeeming value? It cannot even be alchemized into art, into words, into something you can chalk up to an interesting experience because the pain itself, its intensity, is so great that it has woven itself into your system so deeply that there is no way to objectify or push it outside or find its beauty within. That is the pain I’m feeling now. It's so bad, it's useless. The only lesson I will ever derive from this pain is how bad pain can be.”

“Mental illness is so much more complicated than any pill that any mortal could invent ”

“I wanted so much to forget the past, but it wouldn't go away, it hung around like an open wound that refused to scar over, an open window that no amount of muscle could shut.”