“Being human totally sucks most of the time. Videogames are the only thing that make life bearable.”

“She grinned. "Don't you want to build a huge interstellar spaceship, load it full of videogames, junk food, and comfy couches, and then get the hell out of here?" "I'm up for that, too," I said. "if it means I get to spend the rest of my life with you.”

“You know you've totally screwed up your life when your whole world turns to shit and the only person you have to talk to is your system agent software!”

“You were born at a pretty crappy time in history. And it looks like things are only gonna get worse from here on out.”

“You're probably wondering what's going to happen to you. That's easy. The same thing is going to happen to you that has happened to every other human being who has ever lived. You're going to die. We all die. That's just how it is.”

“I wish someone had just told me the truth right up front, as soon as I was old enough to understand it. I wish someone had just said: “Here’s the deal, Wade. You’re something called a ‘human being.’ That’s a really smart kind of animal. Like every other animal on this planet, we’re descended from a single-celled organism that lived millions of years ago. This happened by a process called evolution, and you’ll learn more about it But trust me, that’s really how we all got here. There’s proof of it everywhere, buried in the rocks. That story you heard? About how we were all created by a super-powerful dude named God who lives up in the sky? Total bullshit. The whole God thing is actually an ancient fairy tale that people have been telling one another for thousands of years. We made it all up. Like Santa Claus and the Easter Bunny. “Oh, and by the way … there’s no Santa Claus or Easter Bunny. Also bullshit. Sorry, kid Deal with it.”

“I would argue that masturbation is the human animal's most important adaptation. The very cornerstone of our technological civilization. Our hands evolved to grip tools, all right—including our own. You see, thinkers, inventors, and scientists are usually geeks, and geeks have a harder time getting laid than anyone. Without the built-in sexual release valve provided by masturbation, it's doubtful that early humans would have ever mastered the secrets of fire or discovered the wheel. And you can bet that Galileo, Newton, and Einstein never would have made their discoveries if they hadn't first been able to clear their heads by slapping the salami (or "knocking a few protons off the old hydrogen atom"). The same goes for Marie Curie. Before she discovered radium, you can be certain she first discovered the little man in the canoe.”