“Star Trek was an attempt to say that humanity will reach maturity and wisdom on the day that it begins not just to tolerate, but take a special delight in differences in ideas and differences in life forms. […] If we cannot learn to actually enjoy those small differences, to take a positive delight in those small differences between our own kind, here on this planet, then we do not deserve to go out into space and meet the diversity that is almost certainly out there.”

“If man is to survive, he will have learned to take a delight in the essential differences between men and between cultures. He will learn that differences in ideas and attitudes are a delight, part of life's exciting variety, not something to fear.”

“I handed them a script and they turned it down. It was too controversial. It talked about concepts like, 'Who is God?' The Enterprise meets God in space; God is a life form, and I wanted to suggest that there may have been, at one time in the human beginning, an alien entity that early man believed was God, and kept those legends. But I also wanted to suggest that it might have been as much the Devil as it was God. After all, what kind of god would throw humans out of Paradise for eating the fruit of the Tree of Knowledge. One of the Vulcans on board, in a very logical way, says, 'If this is your God, he's not very impressive. He's got so many psychological problems; he's so insecure. He demands worship every seven days. He goes out and creates faulty humans and then blames them for his own mistakes. He's a pretty poor excuse for a supreme being.”

“For most people, religion is nothing more than a substitute for a malfunctioning brain. If people need religion, ignore them and maybe they will ignore you, and you can go on with your life. It wasn't until I was beginning to do Star Trek that the subject of religion arose. What brought it up was that people were saying that I would have a chaplain on board the Enterprise. I replied, "No, we don't.”

“It is the struggle itself that is most important. We must strive to be more than we are. It does not matter that we will not reach our ultimate goal. The effort itself yields its own reward.”

“There was much to put out of his mind. Why was it difficult to forget Chekov's astonished delight which greeted him at the command airlock when he boarded. And on the bridge - Kirk! The mere name made Spock groan inwardly as he remembered what it had cost him to turn away from that welcome. T'hy'la!”

“Reality is incredibly larger, infinitely more exciting, than the flesh and blood vehicle we travel in here. If you read science fiction, the more you read it the more you realize that you and the universe are part of the same thing. Science knows still practically nothing about the real nature of matter, energy, dimension, or time; and even less about those remarkable things called life and thought. But whatever the meaning and purpose of this universe, you are a legitimate part of it. And since you are part of the all that is, part of its purpose, there is more to you than just this brief speck of existence. You are just a visitor here in this time and this place, a traveler through it.”