“Skepticism is thus a resting-place for human reason, where it can reflect upon its dogmatic wanderings and make survey of the region in which it finds itself, so that for the future it may be able to choose its path with more certainty. But it is no dwelling-place for permanent settlement. Such can be obtained only through perfect certainty in our knowledge, alike of the objects themselves and of the limits within which all our knowledge of objects is enclosed.”

“Philosophy, though unable to tell us with certainty what is the true answer to the doubts which it raises, is able to suggest many possiblities which enlarge our thoughts and free them from the tyranny of custom. Thus, while diminishing our feeling of certainty as to what things are, it greatly increases our knowledge as to what the may be; it removes the somewhat arrogant dogmatism of those who have never travelled into the region of liberating doubt, and it keeps alive our sense of wonder by showing familar things in an unfamilar aspect”

“Our aim as scientists is objective truth; more truth, more interesting truth, more intelligible truth. We cannot reasonably aim at certainty. Once we realize that human knowledge is fallible, we realize also that we can never be completely certain that we have not made a mistake.”

“We confess knowledge without certainty, truth without objectivity.”

“It is precisely this refusal of the Cartesian paradigm that characterizes Radical Orthodoxy, which seeks to reanimate the account of knowledge offered by Augustine and Aquinas. On this ancient-medieval-properly-postmodern model, we rightly give up pretensions to absolute knowledge or certainty, but we do not thereby give up on knowledge altogether. Rather, we can properly confess that we know God was in Christ reconciling the world to himself, but such knowledge rests on the gift of (particular, special) revelation, is not universally objective or demonstrable, and remains a matter of interpretation and perspective (with a significant appreciation for the role of the Spirit's regeneration and illumination as a condition for knowledge). We confess knowledge without certainty, truth without objectivity.”

“The Enlightenment may have indeed outlived its usefulness, but it is only through Reason's protocols that one can make a coherent case for Reason's limitations. O ye of little skepticism, kindly acknowledge your debt to that idiom on which you so glibly heap scorn.”