“That was when Leonard realized something crucial about depression. The smarter you were, the worse it was. The sharper your brain, the more it cut you up.”

“...between addiction and depression? Depression a lot worse. Depression ain't something you just get OFF of. You can't get CLEAN from depression. Depression be like a bruise that never goes away. A bruise in your MIND. You just got to be careful not to touch where it hurts. It always be there, though.”

“One thing I learned, between addiction and depression? Depression a lot worse. Depression ain't something you just get off of. You can't get clean from depression. Depression be like a bruise that never goes away. A bruise in your mind. You just got to be careful not to touch where it hurts. It always be there, though.Darlene, in The Marriage Plot”

“The more she thought about it, the more Madeleine understood that extreme solitude didn't just describe the way she was feeling about Leonard. It explained how she'd always felt when she was in love. It explained what love was like and, just maybe, what was wrong with it.”

“If you grew up in a house where you weren't loved, you didn't know there was an alternative. If you grew up with emotionally stunted parents, who were unhappy in their marriage and prone to visit that unhappiness on their children, you didn't know they were doing this. It was just your life. If you had an accident, at the age of four, when you were supposed to be a big boy, and were later served a plate of feces at the dinner table - if you were told to eat it because you liked it, didn't you, you must like it or you wouldn't have so many accidents - you didn't know that this wasn't happening in the other houses in your neighborhood. If your father left your family, and disappeared, never to return, and your mother seemed to resent you, as you grew older, for being the same sex as your father, you had no one to turn to. In all these cases, the damage was done before you knew you were damaged. The worst part was that, as the years passed, these memories became, in the way you kept them in a secret box in your head, taking them out every so often to turn them over and over, something like dear possessions. They were the key to your unhappiness. The were the evidence that life wasn't fair. If you weren't a lucky child, you didn't know you weren't lucky until you got older. And then it was all you ever thought about.”

“But this was the thought of a depressive. An aspiring depressive, at the time. That was the odd thing about Leonard’s disease, the almost pleasurable way it began. At first his dark moods were closer to melancholy than to despair. There was something enjoyable about wandering around the city alone, feeling forlorn. There was even a sense of superiority, of being right, in not liking the things other kids liked.”

“They said nothing and our parents said nothing, so we sensed how ancient they were, how accustomed to trauma, depressions, and wars. We realized that the version of the world they rendered for us was not the world they really believed in, and for all their caretaking and bitching about crabgrass they didn't give a damn about lawns.”