“Negro Slavery is an evil of Colossal magnitude and I am utterly averse to the admission of Slavery into the Missouri Territories.”

“The whole drama of the world is such tragedy that I am weary of the spectacle.”

“There is nothing which I dread so much as a division of the republic into two great parties, each arranged under its leader, and concerting measures in opposition to each other. This, in my humble apprehension, is to be dreaded as the greatest political evil under our Constitution.”

“It is more important that innocence be protected than it is that guilt be punished, for guilt and crimes are so frequent in this world that they cannot all be punished.But if innocence itself is brought to the bar and condemned, perhaps to die, then the citizen will say, 'whether I do good or whether I do evil is immaterial, for innocence itself is no protection,' and if such an idea as that were to take hold in the mind of the citizen that would be the end of security whatsoever.”

“There are persons whom in my heart I despise, others I abhor. Yet I am not obliged to inform the one of my contempt, nor the other of my detestation. This kind of dissimulation...is a necessary branch of wisdom, and so far from being immoral...that it is a duty and a virtue.”

“I am bold to Say that neither you nor I, will live to See the Course which 'the Wonders of the Times' will take. Many Years, and perhaps Centuries must pass, before the current will acquire a Settled direction... yet Platonic, Pythagoric, Hindoo, and cabalistic Christianity, which is Catholic Christianity, and which has prevailed for 1,500 years, has received a mortal wound, of which the monster must finally die. Yet so strong is his constitution, that he may endure for centuries before he expires.{Letter to Thomas Jefferson, July 16 1814}”

“Even mighty states and kingdoms are not exempted. If we look into history, we shall find some nations rising from contemptible beginnings and spreading their influence, until the whole globe is subjected to their ways. When they have reached the summit of grandeur, some minute and unsuspected cause commonly affects their ruin, and the empire of the world is transferred to some other place. Immortal Rome was at first but an insignificant village, inhabited only by a few abandoned ruffians, but by degrees it rose to a stupendous height, and excelled in arts and arms all the nations that preceded it. But the demolition of Carthage (what one should think should have established is in supreme dominion) by removing all danger, suffered it to sink into debauchery, and made it at length an easy prey to Barbarians.England immediately upon this began to increase (the particular and minute cause of which I am not historian enough to trace) in power and magnificence, and is now the greatest nation upon the globe.Soon after the reformation a few people came over into the new world for conscience sake. Perhaps this (apparently) trivial incident may transfer the great seat of empire into America. It looks likely to me. For if we can remove the turbulent Gallics, our people according to exactest computations, will in another century, become more numerous than England itself. Should this be the case, since we have (I may say) all the naval stores of the nation in our hands, it will be easy to obtain the mastery of the seas, and then the united force of all Europe will not be able to subdue us. The only way to keep us from setting up for ourselves is to disunite us. Divide et impera. Keep us in distinct colonies, and then, some great men from each colony, desiring the monarchy of the whole, they will destroy each others' influence and keep the country in equilibrio.Be not surprised that I am turned into politician. The whole town is immersed in politics.”