“The whole drama of the world is such tragedy that I am weary of the spectacle.”

“Even mighty states and kingdoms are not exempted. If we look into history, we shall find some nations rising from contemptible beginnings and spreading their influence, until the whole globe is subjected to their ways. When they have reached the summit of grandeur, some minute and unsuspected cause commonly affects their ruin, and the empire of the world is transferred to some other place. Immortal Rome was at first but an insignificant village, inhabited only by a few abandoned ruffians, but by degrees it rose to a stupendous height, and excelled in arts and arms all the nations that preceded it. But the demolition of Carthage (what one should think should have established is in supreme dominion) by removing all danger, suffered it to sink into debauchery, and made it at length an easy prey to Barbarians.England immediately upon this began to increase (the particular and minute cause of which I am not historian enough to trace) in power and magnificence, and is now the greatest nation upon the globe.Soon after the reformation a few people came over into the new world for conscience sake. Perhaps this (apparently) trivial incident may transfer the great seat of empire into America. It looks likely to me. For if we can remove the turbulent Gallics, our people according to exactest computations, will in another century, become more numerous than England itself. Should this be the case, since we have (I may say) all the naval stores of the nation in our hands, it will be easy to obtain the mastery of the seas, and then the united force of all Europe will not be able to subdue us. The only way to keep us from setting up for ourselves is to disunite us. Divide et impera. Keep us in distinct colonies, and then, some great men from each colony, desiring the monarchy of the whole, they will destroy each others' influence and keep the country in equilibrio.Be not surprised that I am turned into politician. The whole town is immersed in politics.”

“Negro Slavery is an evil of Colossal magnitude and I am utterly averse to the admission of Slavery into the Missouri Territories.”

“Why have I not genius to start some new thought? Some thing that will surprise the world?”

“There are persons whom in my heart I despise, others I abhor. Yet I am not obliged to inform the one of my contempt, nor the other of my detestation. This kind of dissimulation...is a necessary branch of wisdom, and so far from being immoral...that it is a duty and a virtue.”

“Twenty times in the course of my late reading have I been on the point of breaking out, 'This would be the best of all possible worlds, if there were no religion in it!!!”

“We think ourselves possessed, or at least we boast that we are so, of liberty of conscience on all subjects and of the right of free inquiry and private judgment in all cases, and yet how far are we from these exalted privileges in fact. There exists, I believe, throughout the whole Christian world, a law which makes it blasphemy to deny, or to doubt the divine inspiration of all the books of the Old and New Testaments, from Genesis to Revelations. In most countries of Europe it is punished by fire at the stake, or the rack, or the wheel. In England itself, it is punished by boring through the tongue with a red-hot poker. In America it is not much better; even in our Massachusetts, which, I believe, upon the whole, is as temperate and moderate in religious zeal as most of the States, a law was made in the latter end of the last century, repealing the cruel punishments of the former laws, but substituting fine and imprisonment upon all those blasphemies upon any book of the Old Testament or New. Now, what free inquiry, when a writer must surely encounter the risk of fine or imprisonment for adducing any arguments for investigation into the divine authority of those books? Who would run the risk of translating Volney's Recherches Nouvelles? Who would run the risk of translating Dupuis? But I cannot enlarge upon this subject, though I have it much at heart. I think such laws a great embarrassment, great obstructions to the improvement of the human mind. Books that cannot bear examination, certainly ought not to be established as divine inspiration by penal laws... but as long as they continue in force as laws, the human mind must make an awkward and clumsy progress in its investigations. I wish they were repealed.{Letter to Thomas Jefferson, January 23, 1825}”