“A guy needs somebody―to be near him. A guy goes nuts if he ain't got nobody. Don't make no difference who the guy is, long's he's with you. I tell ya, I tell ya a guy gets too lonely an' he gets sick.”

“I ain't got no people. I seen the guys that go around on the ranches alone. That ain't no good. They don't have no fun. After a long time they get mean. They get wantin' to fight all the time. . . 'Course Lennie's a God damn nuisance most of the time, but you get used to goin' around with a guy an' you can't get rid of him.”

“I seen it over an' over—a guy talkin' to another guy and it don't make no difference if he don't hear or understand. The thing is, they're talkin', or they're settin' still not talkin'. It don't make no difference, no difference. [...] George can tell you screwy things, and it don't matter. It's just the talking. It's just bein' with another guy. That's all.”

“I guess she's just nuts,' he said. 'And if she's nuts, a guy's got to do nuts things. You don't think you could say the hell with her?”

“Guy don't need no sense to be a nice fella. Seems to me sometimes it jus' works the other way around. Take a real smart guy and he ain't hardly ever a nice fella.”

“I like a lot of talk in a book and I don't like to have nobody tell me what the guy that's talking looks like. I want to figure out what he looks like from the way he talks”

“George's voice became deeper. He repeated his words rhythmically as though he had said them many times before. 'Guys like us, that work on ranches, are the loneliest guys in the world. They got no family. They don't belong no place. They come to a ranch an' work up a stake, and the first thing you know they're poundin' their tail on some other ranch. They ain't got nothing to look ahead to.”