“Silver is forty-four years old, if you can believe it, out of shape, and depressed—although he doesn’t know if you call it depression when you have good reason to be; maybe then you’re simply sad, or lonely, or just painfully aware, on a daily basis, of all the things you can never get back.”

“I never felt like that before. Maybe it could be depression, like you get. I can understand how you suffer now when you're depressed; I always thought you liked it and I thought you could have snapped yourself out any time, if not alone then by means of the mood organ. But when you get that depressed you don't care. Apathy, because you've lost a sense of worth. It doesn't matter whether you feel better because you have no worth.”

“The movies make the brooding guy the hero – the guy with problems the guy who carries a gun, the gun with unresolved anger, the guy with a chip on his shoulder, the guy who’s a vampire – and they tell you that you can have the mythical happy ending with that same brooding guy. But in reality, the brooding guy is cranky. He doesn’t reply to emails. He doesn’t call. He’s only half there when you’re talking to him, and he doesn’t chase you when you run. You feel insecure all the time. You get needy and sad and you hate yourself got being needy. If you don’t know why he’s brooding, you’re shut out. And if you do know why he’s brooding, you’re still shut out. (Because he’s busy brooding.)”

“When you're sad or depressed, you might as well get something done," Lydia always said. "Pretty soon, you're not sad or depressed, and darned if things aren't done.”

“if you don't know what to do in this life and you feel depressed,lonely and sad,you should look up into the sky and you will find the answer”

“One thing I learned, between addiction and depression? Depression a lot worse. Depression ain't something you just get off of. You can't get clean from depression. Depression be like a bruise that never goes away. A bruise in your mind. You just got to be careful not to touch where it hurts. It always be there, though.Darlene, in The Marriage Plot”