“When you’re telling a story, you’re trying to connect to people in a particular way … The way in which you guys have inhabited this world, this universe, has made you part of it, part of the story. You are living in Firefly. When I see you guys, I don’t think the show is off the air. I don’t think there’s a show; I think that’s what the world is like. … The story is our lives.”

“Whedon: Studios will tell you: A woman cannot headline an action movie. After The Hunger Games they might stop telling you that a little bit. Whatever you think of the movie, it’s done a great service. And after The Avengers, I think it’s changing.Johansson: A lot of the female superhero movies just suck really badly.Whedon: The suck factor is not small.Johansson: They are really not well made, and already you’re fighting against the tide. There are a couple [female-driven action movies] that have worked-ish, don’t you think?Hemsworth: Angelina Jolie tends to do it pretty well, as the dominant female.Jackson: They got to get The Pro to the screen!Whedon: [Groaning] See, that is the problem. Sam is the problem!Jackson: I love that book!Whedon: [Reluctantly] The Pro is hilarious.Jackson: The Pro’s hilarious. [To the group] You ever see or hear of it?Johansson: No, what’s The Pro?Jackson: It’s [a comic book] about a hooker who gets super powers!Johansson: [Pauses] That is exactly the problem right there.Whedon: That’s why I wasn’t going to bring up The Pro!(From an Entertainment Weekly interview)”

“It is the most fun I’m ever going to have. I love to write. I love it. I mean, there’s nothing in the world I like better, and that includes sex, probably because I’m so very bad at it. It’s the greatest peace when I’m in a scene, and it’s just me and the character, that’s it, that’s where I want to live my life.”

“There are certain human truths, like death, that nobody gets to escape, and pain, which everybody not only feels but needs. You have to go through it. So for everybody, at some point—very often for teenagers—the world is a terrible place. The world is a giant, awful black hole of evil conspiracy. Sometimes that’s because you have perspective on what the world’s really like, and sometimes it’s because you’ve completely lost perspective and you’re having a terrible day. But no matter what, everybody shares that feeling, and life is kind of about your ways around that, your ways around certain truths.”

“Ain't all buttons and charts, little albatross. Know what the first rule of flying is? Well I s'pose you do, since you already know what I'm 'bout to say.I do. But I like to hear you say it.Love. Can know all the math in the 'verse but take a boat in the air that you don't love? She'll shake you off just as sure as a turn in the worlds. Love keeps her in the air when she oughta fall down...tell you she's hurtin' 'fore she keens...makes her a home.”

“I’m assuming you’re as mystified by this as the rest of us, Rasputin. No. I’m not. I have been planning to destroy the Breakworld since I was a child.[silence]This is why I don’t make so many jokes. I never know when is good.”

“The times are chaotic. For me, I would hope that people look at [Angel] and gain strength by it. With everything that I do, I hope that they see people struggling to live decent, moral lives in a completely chaotic world. They see how hard it is, how often they fail, and how they get up and keep trying. That, to me, is the most important message I'm ever going to tell.”