“The beginning of wisdom is the statement 'I don't know'. The person who cannot make that statement is one who will never learn anything.”

“Who's the genius who thought replacing Dick Clark with Ryan Seacrest was a good idea?”

“... I'd rather be prepared for one we don't have to fight than not be prepared for one we have to.”

“No, he focused on the one thing that he knew would keep him grounded the way the demon said he'd need to be."Take your brother outside as fast as you can - don't look back. Now, Dean, go!" Sam's not dying. Not on my watch. You protect your family no matter what.I'm coming for you, Sammy. Just hold tight.And don't look back.He opened his eyes. Behind him, he could hear Kat's voice muttering an incantation in a language he didn't recognize. It wasn't Latin, certainly. Since it was demon magic, it was probably some language that was even more dead than Latin.The chanting stopped.Dean screamed.”

“The world tells us what we need to know when we are ready to know it and not before. That's the way of things.”

“Life was, in fact, cheap.If life was such a glorious, magnificent, wonderful thing, then it wouldn't be so easy to take it away.If life was a great gift, then he wouldn't be able to kill a fellow human being with one hand...”

“And the next time Ash needs a favor, he can go bite me.”