“Just about every adult human being back then had a brain weighing about three kilogrammes! There was no end to the evil schemes that a thought machine that oversized couldn't imagine and execute. So I raise this question, although there is nobody around to answer it: Can it be doubted that three-kilogramme brains were once nearly fatal defects in the evolution of the human race?”

“I was taught that the human brain was the crowning glory of evolution so far, but I think it's a very poor scheme for survival. ”

“What made marriage so difficult back then was yet again that instigator of so many other sorts of heartbreak: the oversize brain.”

“As Mary delivered what was to be her last lecture about the Galapagos Islands, she would be stopped mid-sentence for five seconds by a doubt which, if expressed in words, might have come out something like this: "Maybe I'm just a crazy lady who had wandered off the street and into this classroom and started explaining the mysteries of life to these people. And they believe me, although I am utterly mistaken about simply everything."She had to wonder, too, about all the supposedly great teachers of the past, who, although their brains were healthy, had turned out to be as wrong as Roy about what was really going on.”

“The book was Maniacs in the Fourth Dimension, by Kilgore Trout. It was about people whose mental diseases couldn't be treated because the causes of the diseases were all in the fourth dimension, and three-dimensional Earthling doctors couldn't see those causes at all, or even imagine them.”

“As for myself: I had come to the conclusion that there was nothing sacred about myself or any human being, that we were all machines, doomed to collide and collide and collide. For want of anything better to do, we became fans of collisions. Sometimes I wrote well about collisions, which meant I was a writing machine in good repair. Sometimes I wrote badly, which meant I was a writing machine in bad repair. I no more harbored sacredness than did a Pontiac, a mousetrap, or a South Bend Lathe.”

“More and more people back then, and not just Andrew MacIntosh, had found ensuring the survival of the human race a total bore.”