“It is straightforward—and never mind, for now, about plagues and famines: if God existed, and if he cared for humankind, he would never have given us religion.”

“He was an artist when he saw society: it never crossed his mind that society had to be like this; had any right, had any business being like this. A car in the street. Why? Why cars? This is what an artist has to be: harassed to the point of insanity or stupefaction by first principles.”

“Richard's bookshelves weren't alphabetized. He never had time to alphabetize them. He was always too busy- looking for books he couldn't find.”

“Is it a war we are fighting, a war against health, against life and love? My condition is a torn condition. Every day, the dispensing of existence. I see the face of suffering. Its face is fierce and distant and ancient.There's probably a straightforward explanation for the impossible weariness I feel. A perfectly straightforward explanation. It is a mortal weariness. Maybe I'm tired of being human, if human is what I am. I'm tired of being human.”

“There is a Western phenomenon called the male midlife crisis. Very often it is heralded by divorce. What history might have done to you, you bring about on purpose: separation from woman and child. Don’t tell me that such men aren’t tasting the ancient flavors of death and defeat.In America, with divorce achieved, the midlifer can expect to be more recreational, more discretionary. He can almost design the sort of crisis he is going to have: motorbike, teenage girlfriend, vegetarianism, jogging, sports car, mature boyfriend, cocaine, crash diet, powerboat, new baby, religion, hair transplant.Over here, now, there’s no angling around for your male midlife crisis. It is brought to you and it is always the same thing. It is death.”

“Sex is hard to write about because you lose the universal and succumb to the particular. We all have our different favorites. Good sex is impossible to write about. Lawrence and Updike have given it their all, and the result is still uneasy and unsure. It may be that good sex is something fiction just can't do--like dreams. Most of the sex in my novels is absolutely disastrous. Sex can be funny, but not very sexy.”

“And there was something that frightened me much more. If I went to the doctor's tomorrow, and was cured by, say, the weekend, there'd be no relief from anxiety, just different anxiety. Even as the antibiotics hosed down my genitals, the mind's bacteria would be forming new armies. I'd come up with something to get me down...Was this the case with everyone -- everyone, that is, who wasn't already a thalidomide baked-bean, or a gangrenous imbecile, or degradingly poor, or irretrievably ugly, and would therefore have pretty obvious targets for their worries? If so, the notion of 'having problems' -- or 'having a harder life than most people', or 'having a harder life than you usually had' -- was spurious. You don't have problems, only a capacity for feeling anxious about them, which shifts and jostles but doesn't change.”