“Mr. L. did not get better all at once. He had first to experience cycles of separations, dreams, depressions, and insights—the repetition, or 'working through,' required for long-term neuroplastic change. New ways of relating had to be learned, wiring new neurons together, and old ways of responding had to be unlearned, weakening neuronal links. Because Mr. L. had linked the ideas of separation and death, they were wired together in his neuronal networks. Now that he was conscious of his association, he could unlearn it.”

“Psychotherapy works by going deep into the brain and its neurons and changing their structure by turning on the right genes. Psychiatrist Dr. Susan Vaughan has argued that the talking cure works by "talking to neurons," and that an effective psychotherapist or psychoanalyst is a "microsurgeon of the mind" who helps patients make needed alterations in neuronal networks.”

“There was a time when a new deputy tried to teach Mr. Fruit about the difference between a red and a green light, but Mr. Fruit had resisted all efforts to reorder what he had been doing perfectly well for many years. He had not only monitored the comings and goings of the town, his presence softened the ingrained evil that flourished along the invisible margins of the town’s consciousness. Any community can be judged in its humanity or corruption by how it manages to accommodate the Mr. Fruits of the world. Colleton simply adjusted itself to Mr. Fruit’s harmonies and ordinations. He did whatever he felt was needed and he did it with style. “That’s the Southern way” my grandmother said. “That’s the nice way.”

“Kandel argues that when psychotherapy changes people, 'it presumably does so through learning, by producing changes in gene expression that alter the strength of synaptic connections, and structural changes that alter the anatomical pattern of interconnections between nerve cells of the brain.' Psychotherapy works by going deep into the brain and its neurons and changing their structure by turning on the right genes. Psychiatrist Dr. Susan Vaughan has argued that the talking cure works by 'talking to neurons,' and that an effective psychotherpist or psychoanalyst is a 'microsurgeon of the mind' who helps patients make needed alterations in neuronal networks.”

“Mr. Malfoy is new to the business of having ideas, and so when he has one, he becomes proud of himself for having it. He has not yet had enough ideas to unflinchingly discard those that are beautiful in some aspects and impractical in others; he has not yet acquired confidence in his own ability to think of better ideas as he requires them. What we are seeing here is not Mr. Malfoy's best idea, I fear, but rather his only idea.”

“Mr L Prosser was, as they say, only human. In other words he was a carbon-based life form descended from an ape. More specifically he was forty, fat and shabby and worked for the local council. Curiously enough, though he didn't know it, he was also a direct male-line descendant of Genghis Khan, though intervening generations and racial mixing had so juggled his genes that he had no discernible Mongoloid characteristics, and the only vestiges left in Mr L Prosser of his mighty ancestry were a pronounced stoutness about the tum and a predilection for little fur hats.”