“The exegesis Fat labored on month after month struck me as a Pyrrhic victory if there ever was one — in this case an attempt by a beleaguered mind to make sense out of the inscrutable. Perhaps this is the bottom line to mental illness: incomprehensible events occur; your life becomes a bin for hoax-like fluctuations of what used to be reality. And not only that — as if that weren't enough — but you, like Fat, ponder forever over these fluctuations in an effort to order them into a coherency, when in fact the only sense they make is the sense you impose on them, out of necessity to restore everything into shapes and processes you can recognize. The first thing to depart in mental illness is the familiar. And what takes its place is bad news because not only can you not understand it, you also cannot communicate it to other people. The madman experiences something, but what it is or where it comes from he does not know.”

“The inanity of her remark infuriated him. 'Good grief don't you understand Janet? At this point I'm thoroughly delusional. I'm as mentally ill as it's possible to be. It's incredible that I can communicate with you at all. It's a credit to my ego-strength that I'm not at this point totally autistic.”

“I did not tell Fat this, but technically he had become a Buddha. It did not seem to me like a good idea to let him know. After all, if you are a Buddha you should be able to figure it out for yourself.”

“You know what the doctor said to me to cheer me up?" Fat said. "There are worse diseases than cancer.""Did he show you slides?"We both laughed. When you are nearly crazy with grief, you laugh at what you can.”

“In a sense, the better you adapt to school the less your chances are of later adapting to the actual world. So I figure, the worse you adapt to school, the better you will be able to handle reality when you finally manage to get loose at last from school, if that ever happens. But I guess I have what in the military they call a 'poor attitude,' which means 'shape up or ship out.' I always elected to ship out.”

“To save one life, Mr Tagomi had to take two. The logical, balanced mind cannot make sense of that”

“At that moment, when I had the TV sound off, I was in a 382 mood; I had just dialed it. So although I heard the emptiness intellectually, I didn't feel it. My first reaction consisted of being grateful that we could afford a Penfield mood organ. But then I realized how unhealthy it was, sensing the absence of life, not just in this building but everywhere, and not reacting—do you see? I guess you don't. But that used to be considered a sign of mental illness; they called it 'absence of appropriate affect.' So I left the TV sound off and I sat down at my mood organ and I experimented. And I finally found a setting for despair. So I put it on my schedule for twice a month; I think that's a reasonable amount of time to feel hopeless about everything, about staying here on Earth after everybody who's smart has emigrated, don't you think?”