“Physics is like sex: sure, it may give some practical results, but that's not why we do it.”

“Science is like sex: sometimes something useful comes out, but that is not the reason we are doing it. ”

“I want to build a billion tiny factories, models of each other, which are manufacturing simultaneously… The principles of physics, as far as I can see, do not speak against the possibility of maneuvering things atom by atom. It is not an attempt to violate any laws; it is something, in principle, that can be done; but in practice, it has not been done because we are too big.”

“How can we tell whether the rules which we "guess" at are really right if we cannot analyze the game very well? There are, roughly speaking, three ways.First, there may be situations where nature has arranged, or we arrange nature, to be simple and to have so few parts that we can predict exactly what will happen, and thus we can check how our rules work. (In one corner of the board there may be only a few chess pieces at work, and that we can figure out exactly.)A second good way to check rules is in terms of less specific rules derived from them. For example, the rule on the move of a bishop on a chessboard is that it moves only on the diagonal. One can deduce, no matter how many moves may be made, that a certain bishop will always be on a red square. So, without being able to follow the details, we can always check our idea about the bishop's motion by finding out whether it is always on a red square. Of course it will be, for a long time, until all of a sudden we find that it is on a black square (what happened of course, is that in the meantime it was captured, another pawn crossed for queening, and it turned into a bishop on a black square). That is the way it is in physics. For a long time we will have a rule that works excellently in an over-all way, even when we cannot follow the details, and then some time we may discover a new rule. From the point of view of basic physics, the most interesting phenomena are of course in the new places, the places where the rules do not work—not the places where they do work! That is the way in which we discover new rules.The third way to tell whether our ideas are right is relatively crude but prob-ably the most powerful of them all. That is, by rough approximation. While we may not be able to tell why Alekhine moves this particular piece, perhaps we can roughly understand that he is gathering his pieces around the king to protect it, more or less, since that is the sensible thing to do in the circumstances. In the same way, we can often understand nature, more or less, without being able to see what every little piece is doing, in terms of our understanding of the game.”

“Why make yourself miserable saying things like, "Why do we have such bad luck? What has God done to us? What have we done to deserve this?" - all of which, if you understand reality and take it completely into your heart, are irrelevant and unsolvable. They are just things that nobody can know. Your situation is just an accident of life.”

“Scientific knowledge is a body of statements of varying degrees of certainty -- some most unsure, some nearly sure, none absolutely certain.”

“A poet once said, 'The whole universe is in a glass of wine.' We will probably never know in what sense he meant it, for poets do not write to be understood. But it is true that if we look at a glass of wine closely enough we see the entire universe. There are the things of physics: the twisting liquid which evaporates depending on the wind and weather, the reflection in the glass; and our imagination adds atoms. The glass is a distillation of the earth's rocks, and in its composition we see the secrets of the universe's age, and the evolution of stars. What strange array of chemicals are in the wine? How did they come to be? There are the ferments, the enzymes, the substrates, and the products. There in wine is found the great generalization; all life is fermentation. Nobody can discover the chemistry of wine without discovering, as did Louis Pasteur, the cause of much disease. How vivid is the claret, pressing its existence into the consciousness that watches it! If our small minds, for some convenience, divide this glass of wine, this universe, into parts -- physics, biology, geology, astronomy, psychology, and so on -- remember that nature does not know it! So let us put it all back together, not forgetting ultimately what it is for. Let it give us one more final pleasure; drink it and forget it all!”