“We are trying to prove ourselves wrong as quickly as possible, because only in that way can we find progress.”

“I can live with doubt and uncertainty and not knowing. I think it is much more interesting to live not knowing than to have answers that might be wrong. If we will only allow that, as we progress, we remain unsure, we will leave opportunities for alternatives. We will not become enthusiastic for the fact, the knowledge, the absolute truth of the day, but remain always uncertain … In order to make progress, one must leave the door to the unknown ajar.”

“So my antagonist said, "Is it impossible that there are flying saucers? Can you prove that it's impossible?" "No", I said, "I can't prove it's impossible. It's just very unlikely". At that he said, "You are very unscientific. If you can't prove it impossible then how can you say that it's unlikely?" But that is the way that is scientific. It is scientific only to say what is more likely and what less likely, and not to be proving all the time the possible and impossible.”

“If instead of arranging the atoms in some definite pattern, again and again repeated, on and on, or even forming little lumps of complexity like the odor of violets, we make an arrangement which is always different from place to place, with different kinds of atoms arranged in many ways, continually changing, not repeating, how much more marvelously is it possible that this thing might behave? Is it possible that that "thing" walking back and forth in front of you, talking to you, is a great glob of these atoms in a very complex arrangement, such that the sheer complexity of it staggers the imagination as to what it can do? When we say we are a pile of atoms, we do not mean we are merely a pile of atoms, because a pile of atoms which is not repeated from one to the other might well have the possibilities which you see before you in the mirror.”

“How can we tell whether the rules which we "guess" at are really right if we cannot analyze the game very well? There are, roughly speaking, three ways.First, there may be situations where nature has arranged, or we arrange nature, to be simple and to have so few parts that we can predict exactly what will happen, and thus we can check how our rules work. (In one corner of the board there may be only a few chess pieces at work, and that we can figure out exactly.)A second good way to check rules is in terms of less specific rules derived from them. For example, the rule on the move of a bishop on a chessboard is that it moves only on the diagonal. One can deduce, no matter how many moves may be made, that a certain bishop will always be on a red square. So, without being able to follow the details, we can always check our idea about the bishop's motion by finding out whether it is always on a red square. Of course it will be, for a long time, until all of a sudden we find that it is on a black square (what happened of course, is that in the meantime it was captured, another pawn crossed for queening, and it turned into a bishop on a black square). That is the way it is in physics. For a long time we will have a rule that works excellently in an over-all way, even when we cannot follow the details, and then some time we may discover a new rule. From the point of view of basic physics, the most interesting phenomena are of course in the new places, the places where the rules do not work—not the places where they do work! That is the way in which we discover new rules.The third way to tell whether our ideas are right is relatively crude but prob-ably the most powerful of them all. That is, by rough approximation. While we may not be able to tell why Alekhine moves this particular piece, perhaps we can roughly understand that he is gathering his pieces around the king to protect it, more or less, since that is the sensible thing to do in the circumstances. In the same way, we can often understand nature, more or less, without being able to see what every little piece is doing, in terms of our understanding of the game.”

“If you thought you were trying to find out more about it because you're gonna get an answer to some deep philosophical question...you may be wrong! It may be that you can't get an answer to that particular question by finding out more about the character of nature. But my interest in science is to simply find out about the world.”

“[Doubt] is not a new idea; this is the idea of the age of reason. This is the philosophy that guided the men who made the democracy that we live under. The idea that no one really knew how to run a government led to the idea that we should arrange a system by which new ideas could be developed, tried out, and tossed out if necessary, with more new ideas bought in - a trial-and-error system. This method was a result of the fact that science was already showing itself to be a successful venture at the end of the eighteenth century. Even then it was clear to socially minded people that the openness of possibilities was an opportunity, and that doubt and discussion were essential to progress into the unknown. If we want to solve a problem that we have never solved before, we must leave the door to the unknown ajar...doubt is not to be feared, but welcomed and discussed.”