“The daughter of Lithuanian immigrants, born with a precocious scientific intellect and a thirst for chemical knowledge, Elion had completed a master's degree in chemistry from New York University in 1941 while teaching high school science during the day and preforming her research for her thesis at night and on the weekends. Although highly qualified, talented, and driven, she had been unable to find a job in an academic laboratory. Frustrated by repeated rejections, she had found a position as a supermarket product supervisor. When Hitchings found Trudy Elion, who would soon become on of the most innovative synthetic chemists of her generation (and a future Nobel laureate), she was working for a food lab in New York, testing the acidity of pickles and the color of egg yolk going into mayonnaise. Rescued from a life of pickles and mayonnaise…”

“In the day school she went to in New York she had long intimate conversations with them all in her imagination, but never in reality.”

“Most of my friends from Columbia are going on to get advanced degrees. And why not? A Ph.D. is the new M.A., a master's is the new bachelor's, a B.A. is the new high school diploma, and a high school diploma is the new smiley-face sticker on your first-grade spelling test.”

“But it did not stop her from wishing that it had all been different. Wishing that she had had the chance to be everything daughters of earls were born to be. Wishing that she'd been raised without a care in the world. Without a doubt in her head that it would someday be her day to sparkle; that she would one day be courted properly - by a man who wanted her for her, not as a spoil from a game of chance.Wishing that she were not so very alone.Not that wishing had ever helped.”

“No domestic dispute between Franny and David had inspired the removal of their wedding rings. She would take hers off at work when she was giving scalp massages. Once she thought she had lost the ring, but she found it in the treatment room on a candleholder David had made for her during a personal failure of a pottery class he had taken the year he lost his job. After she found her ring, she started leaving it at home.”

“It is necessary to find one's own way in New York. New York City is not hospitable. She is very big and she has no heart. She is not charming. She is not sympathetic. She is rushed and noisy and unkempt, a hard, ambitious, irresolute place, not very lively, and never gay. When she glitters she is very, very bright, and when she does not glitter she is dirty. New York does nothing for those of us who are inclined to love her except implant in our hearts a homesickness that baffles us until we go away from her, and then we realize why we are restless. At home or away, we are homesick for New York not because New York used to be better and not because she used to be worse but because the city holds us and we don't know why.”