“The idea that the creative endeavor and mind-altering substances are entwined is one of the great pop-intellectual myths of our time. ... Substance abusing writers are just substance abusers — common garden variety drunks and druggies, in other words. Any claims that the drugs and alcohol are necessary to dull a finer sensibility are just the usual self-serving bullshit. I've heard alcoholic snowplow drivers make the same claim, that they drink to still the demons.”

“The idea that creative endeavor and mind-altering substances are entwined is one of the great pop-intellectual myths of our time.”

“People with family histories of alcoholism tend to have lower levels of endorphins- the endogenous morphine that is responsible for many of our pleasure responses- than do people genetically disinclined to alcoholism. Alcohol will slightly raise the endorphin level of people without the genetic basis for alcoholism; it will dramatically raise the endorphin level of people with that genetic basis. Specialists spend a lot of time formulating exotic hypotheses to account for substance abuse. Most experts point out, strong motivations for avoiding drugs; but there are also strong motivations for taking them. People who claim not to understand why anyone would get addicted to drugs are usually people who haven't tried them or who are genetically fairly invulnerable to them.”

“If he were any other man, I might have suspected him of substance abuse, of being coked up or something. But Barrons was too much a purist for that; his drugs were money, power, and control”

“People are the biggest drug addiction in the world, and I mean that quite literally. Take any single substance abuse problem in the world, and it's dwarfed in comparison to the addiction to feelings and people.”

“As applied to substance abuse, the cognitive approach helps individualsto come to grips with the problems leading to emotional distressand to gain a broader perspective on their reliance on drugs forpleasure and/or relief from discomfort.”