“It's a long way from not having enough serotonin to thinking the world is "stale, flat and unprofitable"; even further to writing a play about a man driven by that thought. ”

“There is thought, and then there is thinking about thoughts, and they don't feel the same.”

“The point is, the brain talks to itself, and by talking to itself changes its perceptions. To make a new version of the not-entirely-false model, imagine the first interpreter as a foreign correspondent, reporting from the world. The world in this case means everything out- or inside our bodies, including serotonin levels in the brain. The second interpreter is a news analyst, who writes op-ed pieces. They read each other's work. One needs data, the other needs an overview; they influence each other. They get dialogues going.INTERPRETER ONE: Pain in the left foot, back of heel.INTERPRETER TWO: I believe that's because the shoe is too tight.INTERPRETER ONE: Checked that. Took off the shoe. Foot still hurts.INTERPRETER TWO: Did you look at it?INTERPRETER ONE: Looking. It's red.INTERPRETER TWO: No blood?INTERPRETER ONE: Nope.INTERPRETER TWO: Forget about it.INTERPRETER ONE: Okay.Mental illness seems to be a communication problem between interpreters one and two.An exemplary piece of confusion.INTERPRETER ONE: There's a tiger in the corner.INTERPRETER TWO: No, that's not a tiger- that's a bureau.INTERPRETER ONE: It's a tiger, it's a tiger!INTERPRETER TWO: Don't be ridiculous. Let's go look at it.Then all the dendrites and neurons and serotonin levels and interpreters collect themselves and trot over to the corner.If you are not crazy, the second interpreter's assertion, that this is a bureau, will be acceptable to the first interpreter. If you are crazy, the first interpreter's viewpoint, the tiger theory, will prevail. The trouble here is that the first interpreter actually sees a tiger. The messages sent between neurons are incorrect somehow. The chemicals triggered are the wrong chemicals, or the impulses are going to the wrong connections. Apparently, this happens often, but the second interpreter jumps in to straighten things out.”

“For many of us, the hospital was as much a refuge as it was a prison. Though we were cut off from the world and all the trouble we enjoyed stirring up out there, we were also cut off from the demands and expectations that had driven us crazy. What could be expected of us now that we were stowed away in a loony bin?”

“Twenty aspirin, a little slit alongside the veins of the arm, maybe even a bad half hour standing on a roof: We've all had those. And somewhat more dangerous things, like putting a gun in your mouth. But you put it there, you taste it, it's cold and greasy, your finger is on the trigger, and you find that a whole world lies between this moment and the moment you've been planning, when you'll pull the trigger. That world defeats you. You put the gun back in the drawer. You'll have to find another way.”

“The debate was wearing me out. Once you've posed that question, it won't go away. I think manypeople kill themselves simply to stop the debate about whether they will or they won't.Anything I thought or did was immediately drawn into the debate. Made a stupid remark--why not killmyself? Missed the bus--better put an end to it all. Even the good got in there. I liked that movie--maybeI shouldn't kill myself.”

“Don't separate the mind from the body. Don't separate even character - you can't. Our unit of existence is a body, a physical, tangible, sensate entity with perceptions and reactions that express it and form it simultaneously.Disease is one of our languages. Doctors understand what disease has to say about itself. It's up to the person with the disease to understand what the disease has to say to her.”