“Trust a witness in all matters in which neither his self-interest, his passions, his prejudices, nor the love of the marvellous is strongly concerned. When they are involved, require corroborative evidence in exact proportion to the contravention of probability by the thing testified.”

“Perhaps the most valuable result of all education is the ability to make yourself do the thing you have to do, when it ought to be done, whether you like it or not. It is the first lesson that ought to be learned and however early a man's training begins, it is probably the last lesson that he learns thoroughly.”

“It is not what we believe, but why we believe it. Moral responsibility lies in diligently weighing the evidence. We must actively doubt; we have to scrutinize our views, not take them on trust. No virtue attached to blindly accepting orthodoxy, however 'venerable'...”

“[Responding to the Bishop of Oxford, Samuel Wilberforce's question whether he traced his descent from an ape on his mother's or his father's side]A man has no reason to be ashamed of having an ape for his grandfather. If there were an ancestor whom I should feel shame in recalling it would rather be a man—a man of restless and versatile intellect—who … plunges into scientific questions with which he has no real acquaintance, only to obscure them by an aimless rhetoric, and distract the attention of his hearers from the real point at issue by eloquent digressions and skilled appeals to religious prejudice.”

“It was badly received by the generation to which it was first addressed, and the outpouring of angry nonsense to which it gave rise is sad to think upon. But the present generation will probably behave just as badly if another Darwin should arise, and inflict upon them that which the generality of mankind most hate—the necessity of revising their convictions. Let them, then, be charitable to us ancients; and if they behave no better than the men of my day to some new benefactor, let them recollect that, after all, our wrath did not come to much, and vented itself chiefly in the bad language of sanctimonious scolds. Let them as speedily perform a strategic right-about-face, and follow the truth wherever it leads.”

“The chess-board is the world; the pieces are the phenomena of the universe; the rules of the game are what we call the laws of Nature. The player on the other side is hidden from us. We know that his play is always fair, and patient. But also we know, to our cost, that he never overlooks a mistake, or makes the smallest allowance for ignorance.”

“I suppose that, so long as the human mind exists, it will not escape its deep-seated instinct to personify its intellectual conceptions. The science of the present day is as full of this particular form of intellectual shadow-worship as is the nescience of ignorant ages. The difference is that the philosopher who is worthy of the name knows that his personified hypotheses, such as law, force and ether, and the like, are merely useful symbols, while the ignorant and the careless take them for adequate expressions of reality.”