“Long-standing togetherness writes permanent changes into a brain's open book. In a relationship, one mind revises another; one heart changes its partner. (144)”

“Describing good relatedness to someone, no matter how precisely or how often, does not inscribe it into the neural networks that inspire love. Self-help books are like car repair manuals: you can read them all day, but doing so doesn't fix a thing. Working on a car means rolling up your sleeves and getting under the hood, and you have to be willing to get dirt on your hands and grease beneath your fingernails. Overhauling emotional knowledge is no spectator sport; it demands the messy experience of yanking and tinkering that comes from a limbic bond. If someone's relationship today bear a troubled imprint, they do so because an influential relationship left its mark on a child's mind. When a limbic connection has established a neural pattern, it takes a limbic connection to revise it.”

“The brevity of mini (psycho)therapies is another efficient forestaller of healing. The neocortex rapidly master didactic information, but the limbic brain takes mountains of repetition. No one expects to play the flute in six lessons or to become fluent in Italian in ten. (189)”

“A therapist who fears dependence will tell his patient, sometimes openly, that the urge to rely is pathologic. In doing so he denigrates a cardinal tool. A parent who rejects a child's desire to depend raises a fragile person. Those children, grown to adulthood, are frequently among those who come for help. Shall we tell them again that no one can find an art to lean on, that each alone must work to ease a private sorrow? Then we shall repeat and experiment already conducted; many know its result only too well. If patient and therapist are to proceed together down a curative path, they must allow limbic regulation and its companion moon, dependence, to make the revolutionary magic. Many therapists believe that reliance fosters a detrimental dependency. Instead, they say, patients should be directed to "do it for themselves" - as if they possess everything but the wit to throw that switch and get on with their lives. But people do not learn emotional modulation as they do geometry or the names of state capitals. They absorb the skill from living in the presence of an adept external modulator, and they learn it implicitly. Knowledge leaps the gap from one mind to the other, but the learner does not experience the transferred information as an explicit strategy. Instead, a spontaneous capacity germinates and becomes a natural part of the self, like knowing how to ride a bike or tie one's shoes. The effortful beginnings fade and disappear from memory. (171)”

“When anxiety becomes problematic, most people try vainly to think their way out of trouble. But worry has its roots in the reptilian brain, minimally responsive to will. As a wise psychoanalyst once remarked of the autonomic nervous system (which carries the outgoing fear messages from the reptilian brain), "It's so far from the head it doesn't even know there is a head." (49)”

“Knowing someone is the first goal of therapy. Modulating emotionality - whether by relatedness or psychopharmacology or both - is second. Therapy's last and most ambitious aim is revising the neural code that directs an emotional life. (176)”

“The person of the therapist is the converting catalyst, not his order or credo, not his spatial location in the room, not his exquisitely chosen words or denominational silences. So long as the rules of a therapeutic system do not hinder limbic transmission - a critical caveat - they remain inconsequential, neocortical distractions. The dispensable trappings of dogma may determine what a therapist thinks he is doing, what he talks about when he talks about therapy, but the agent of change is who he is. (187)”