“Learning how to transform mere ignorance into mystery, simple not knowing into wonder, is a useful skill. Because it turns out that the most important things in this life — why the universe is here instead of not, what happens to us when we die, how the people we love really feel about us — are things we’re never going to know.”

“The Soul Toupee is that thing about ourselves we are most deeply embarrassed by and like to think we have cunningly concealed from the world, but which is, in fact, pitifully obvious to everybody who knows us.”

“This is one reason people need to believe in God—because we want someone to know us, truly, all the way through, even the worst of us.”

“Anytime I hear about another one of us gone berserk, shooting up his ex’s office or drowning her kids to free herself up for her Internet boyfriend, the question I always ask is not, like every other tongue-clucking pundit in the country, how could this have happened? but why doesn't this happen every day?”

“I've demonstrated an impressive resilience in the face of valuable life lessons, and the main thing I seem to have learned from this one is that I am capable of learning nothing from almost any experience, no matter how profound.”

“My feeling toward Republicans is like my feeling about sharks: of course they're stupid and vicious. It's in their nature to be mindless, ravening killing machines. It's nothing personal. They don't know any better. Pretty much the only thing you can do about them is stay out of their waters and, if you're unlucky enough to meet with one, shoot it through its rudimentary brain with a spear gun.”

“It turns out that when there is some conspicuous gap or contradiction at the center of someone's existence, there is probably a very specific, obvious reason for it, and the reason you're avoiding confronting it directly is that it's something you don't want to know.”