“We seem to face an enemy who, no matter how many times we win, will best us in the end. He has so many allies: time, disease, boredom, stupidity, religious quackery, and bad habits.”

“To physically overcome death – is that not the goal? – we must think the unthinkable thoughts and ask unanswerable questions. Yet we must not lose ourselves in abstract vapors of philosophy. Death ahs his concrete allies, we must enlist ours. Never underestimate how much assistance, how much satisfaction, how much comfort, how much soul and transcendence there might be in a well-made taco and a cold bottle of beer. The solution to the ultimate problem may prove to be elemental and quite practical. Philosophers have argued for centuries about how many angels can dance on the head of a pin, but materialists have known all along that it depends on whether they are jitterbugging or dancing cheek to cheek.”

“The enemy of the black is not the white. The enemy of capitalist is not communist, the enemy of homosexual is not heterosexual, the enemy of Jew is not Arab, the enemy of youth is not the old, the enemy of hip is not redneck, the enemy of Chicano is not gringo and the enemy of women is not men. We all have the same enemy. The enemy is the tyranny of the dull mind. The enemy is every expert who practices technocratic manipulation, the enemy is every proponent of standardization and the enemy is every victim who is so dull and lazy and weak as to allow himself to be manipulated and standardized.”

“Nature is not infallible. Nature makes mistakes. That's what evolution is all about: growth by trail and error. Nature can be stupid and cruel. Oh, my, how cruel! That's okay. There's nothing wrong with Nature being dumb and ugly because it is simultaneously--paradoxically--brilliant and superb.But to worship the natural at the exclusion of the unnatural is to practice Organic Fascism--which is what many of my pilgrims practice. And in the best tradition of fascism, they are totally intolerant of those who don't share their beliefs; thus, they foster the very kinds of antagonism and tension that lead to strife, which they, pacifists one and all, claim to abhor. To insist that a woman who paints berry juice on her lips is somehow superior to the woman who wears Revlon lipstick is sophistry; it's smug sophistical skunkshit. Lipstick is a chemical composition, so is berry juice, and they both are effective for decorating the face. If lipstick has advantages over berry juice then let us praise that part of technology that produced lipstick. The organic world is wonderful, bot the inorganic isn't bad, either. The world of plastic and artifice offers its share of magical surprises.A thing is good because it's good, not because it's natural. A thing is bad because it's bad, not because it's artificial. It's not a damn iota better to be bitten by a rattlesnake than shot by a gun.”

“All depression has its roots in self-pity, and all self-pity is rooted in people taking themselves too seriously.”At the time Switters had disputed her assertion. Even at seventeen, he was aware that depression could have chemical causes.“The key word here is roots,” Maestra had countered. “The roots of depression. For most people, self-awareness and self-pity blossom simultaneously in early adolescence. It's about that time that we start viewing the world as something other than a whoop-de-doo playground, we start to experience personally how threatening it can be, how cruel and unjust. At the very moment when we become, for the first time, both introspective and socially conscientious, we receive the bad news that the world, by and large, doesn't give a rat's ass. Even an old tomato like me can recall how painful, scary, and disillusioning that realization was. So, there's a tendency, then, to slip into rage and self-pity, which if indulged, can fester into bouts of depression.”“Yeah but Maestra—”“Don't interrupt. Now, unless someone stronger and wiser—a friend, a parent, a novelist, filmmaker, teacher, or musician—can josh us out of it, can elevate us and show us how petty and pompous and monumentally useless it is to take ourselves so seriously, then depression can become a habit, which, in tern, can produce a neurological imprint. Are you with me? Gradually, our brain chemistry becomes conditioned to react to negative stimuli in a particular, predictable way. One thing'll go wrong and it'll automatically switch on its blender and mix us that black cocktail, the ol’ doomsday daiquiri, and before we know it, we’re soused to the gills from the inside out. Once depression has become electrochemically integrated, it can be extremely difficult to philosophically or psychologically override it; by then it's playing by physical rules, a whole different ball game. That's why, Switters my dearest, every time you've shown signs of feeling sorry for yourself, I've played my blues records really loud or read to you from The Horse’s Mouth. And that’s why when you’ve exhibited the slightest tendency toward self-importance, I’ve reminded you that you and me— you and I: excuse me—may be every bit as important as the President or the pope or the biggest prime-time icon in Hollywood, but none of us is much more than a pimple on the ass-end of creation, so let’s not get carried away with ourselves. Preventive medicine, boy. It’s preventive medicine.”“But what about self-esteem?”“Heh! Self-esteem is for sissies. Accept that you’re a pimple and try to keep a lively sense of humor about it. That way lies grace—and maybe even glory.”

“The word desire suggests that there is something we do not have. If we have everything already, then there can be no desire, for there is nothing left to want. I think that what the Buddha may have been trying to tell us is that we have it all, each of us, all the time; therefore, desire is simply unnecessary.”

“As a grandiose self-deception, war is o’ the same magnitude as religion. We embrace war or religion - usually both at the same time - as a means o’ defeatin’ death, but neither o’ them do a blinkin’ thing but sanction dyin’. Throughout history, Death’s best friend has been a priest with a knife.”