“A phenomenon that a number of people have noted while in deep depression is the sense of being accompanied by a second self — a wraithlike observer who, not sharing the dementia of his double, is able to watch with dispassionate curiosity as his companion struggles against the oncoming disaster, or decides to embrace it. There is a theatrical quality about all this, and during the next several days, as I went about stolidly preparing for extinction, I couldn't shake off a sense of melodrama — a melodrama in which I, the victim-to-be of self-murder, was both the solitary actor and lone member of the audience.”

“date of the award approached, I would not have accepted at all. Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self--to the mediating intellect--as to verge close to being beyond description. It thus remains nearly incomprehensible to those who have not experienced it in its extreme mode, although the gloom, "the blues" which people go through occasionally and associate with the general hassle of everyday existence are of such prevalence that they do give many individuals a hint of the illness in its catastrophic form.”

“Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self -- to the mediating intellect-- as to verge close to being beyond description. It thus remains nearly incomprehensible to those who have not experienced it in its extreme mode.”

“I mean, I don't know much about the Civil War, but whenever I think of that time—I mean, ever since Gone With the Wind I've had these fantasies about those generals, those gorgeous young Southern generals with their tawny mustaches and beards, and hair in ringlets, on horseback. And those beautiful girls in crinoline and pantalettes. You would never know that they ever fucked, from all you're able to read." She paused and squeezed my hand. "I mean, doesn't it just do something to you to think of one of those ravishing girls with that crinoline all in a fabulous tangle, and one of those gorgeous young officers—I mean, both of them fucking like crazy?""Oh yes," I said with a shiver, "oh yes, it does. It enlarges one's sense of history.”

“When I was first aware that I had been laid low by the disease, I felt a need, among other things, to register a strong protest against the word "depression." Depression, most people know, used to be termed "melancholia," a word which appears in English as the year 1303 and crops up more than once in Chaucer, who in his usage seemed to be aware of its pathological nuances. "Melancholia" would still appear to be a far more apt and evocative word for the blacker forms of the disorder, but it was usurped by a noun with a blank tonality and lacking any magisterial presence, used indifferently to describe an economic decline or a rut in the ground, a true wimp of a word for such a major illness.It may be that the scientist generally held responsible for its currency in modern times, a Johns Hopkins Medical School faculty member justly venerated -- the Swiss-born psychiatrist Adolf Meyer -- had a tin ear for the finer rhythms of English and therefore was unaware of the semantic damage he had inflicted for such a dreadful and raging disease. Nonetheless, for over seventy-five years the word has slithered innocuously through the language like a slug, leaving little trace of its intrinsic malevolence and preventing, by its insipidity, a general awareness of the horrible intensity of the disease when out of control.”

“Someday I will understand Auschwitz. This was a brave statement but innocently absurd. No one will ever understand Auschwitz. What I might have set down with more accuracy would have been: Someday I will write about Sophie's life and death, and thereby help demonstrate how absolute evil is never extinguished from the world. Auschwitz itself remains inexplicable. The most profound statement yet made about Auschwitz was not a statement at all, but a response.The query: "At Auschwitz, tell me, where was God?"And the answer: "Where was man?”

“To make matters worse, I was out of a job and had very little money and was self-exiled to Flatbush—like others of my countrymen, another lean and lonesome Southerner wandering amid the Kingdom of the Jews.”