“Edward was at the stage of drunkenness in which the ego glows like a coal, and brilliant people become more inspired, but in which dull people, fired by the same inspiration, become only more dull.”

“The good writing of any age has always been the product of someone's neurosis, and we'd have a mighty dull literature if all the writers that came along were a bunch of happy chuckleheads.”

“date of the award approached, I would not have accepted at all. Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes known to the self--to the mediating intellect--as to verge close to being beyond description. It thus remains nearly incomprehensible to those who have not experienced it in its extreme mode, although the gloom, "the blues" which people go through occasionally and associate with the general hassle of everyday existence are of such prevalence that they do give many individuals a hint of the illness in its catastrophic form.”

“Which is worse, past or future? Neither. I will fold up my mind like a leaf and drift on this stream over the brink. Which will be soon, and then the dark, and then be done with this ugliness...”

“When I was first aware that I had been laid low by the disease, I felt a need, among other things, to register a strong protest against the word "depression." Depression, most people know, used to be termed "melancholia," a word which appears in English as the year 1303 and crops up more than once in Chaucer, who in his usage seemed to be aware of its pathological nuances. "Melancholia" would still appear to be a far more apt and evocative word for the blacker forms of the disorder, but it was usurped by a noun with a blank tonality and lacking any magisterial presence, used indifferently to describe an economic decline or a rut in the ground, a true wimp of a word for such a major illness.It may be that the scientist generally held responsible for its currency in modern times, a Johns Hopkins Medical School faculty member justly venerated -- the Swiss-born psychiatrist Adolf Meyer -- had a tin ear for the finer rhythms of English and therefore was unaware of the semantic damage he had inflicted for such a dreadful and raging disease. Nonetheless, for over seventy-five years the word has slithered innocuously through the language like a slug, leaving little trace of its intrinsic malevolence and preventing, by its insipidity, a general awareness of the horrible intensity of the disease when out of control.”

“Yet if she did not quite exist in the full flood of sunlight, which is the hackneyed metaphor for good health, she was comfortably and safely far away from that abyssal darkness down into which she had nearly strayed.”

“What this country needs... what this great land of ours needs is something to happen to it. Something ferocious and tragic, like what happened to Jericho or the cities of the plain - something terrible I mean, son, so that when the people have been through hellfire and the crucible, and have suffered agony enough and grief, they’ll be people again, human beings, not a bunch of smug contented cows rooting at the trough.”